Yu Chen|Qianyun Liu|Deyin Guo Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China Center for Infection and Immunity Study, School of Medicine, Sun Yat‐sen University, Guangzhou, China Abstract The recent emergence of a novel corona virus (2019‐nCoV), which is causing an out break of unusual viral pneumonia in […]
Viruses originate from RNAs. The sugar in RNA is ribose sugar and is the phosphates based, and they react in the nucleotides to form an ester bond. While not inside a cell or in the process of cell infection, viruses exist as an independent particle known as virions or virus particles. The way the virus […]
Matthew G. Drake1*, Elizabeth R. Bivins-Smith1*, Becky J. Proskocil1, Zhenying Nie1, Gregory D. Scott2, James J. Lee3,Nancy A. Lee4, Allison D. Fryer1, and David B. Jacoby1 Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon; 3 Department of Biochemistry and Molecular Biology, Division of Pulmonary Medicine, and 4 Department of […]
Nutrients 2013, 5, 3964-3974; doi:10.3390 / nu5103964 / ISSN 2072-6643 Abstract: Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or […]
Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis (Review) Laura Toxqui and M. Pilar Vaquero * Abstract: Iron is essential in oxygen transport and participates in many enzymatic systems in the body, with important roles in collagen synthesis and vitamin D metabolism. The relationship between iron and bone health comes from […]
Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1 Palmieri, V Papaleo, V Porcelli, P Scarcia, L Gaita, R Sacco, J Hager, F Rousseau, P Curatolo, B Manzi, R Militerni, C Bravaccio, S Trillo, C Schneider, R Melmed, M Elia, C Lenti, M Saccani, T Pascucci, S Puglisi-Allegra, K-L Reichelt & A M Persico Abstract Autism is a severe developmental disorder, whose pathogenetic underpinnings are […]
Biochimica et Biophysica Acta (BBA) – Molecular Cell Research Volume 1865, Issue 11, Part B, November 2018, Pages 1718-1732 Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways☆ Author links open overlay panelRachel L.NguyenabYuliya V.MedvedevaabdTejasvi E.AyyagariabGalinaSchmunkbJohn JayGargusabc a Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA b […]
Interleukin-1 Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin* Joseph S. Ainscough‡1, G. Frank Gerberick§, Ian Kimber‡, and Rebecca J. Dearman‡ From the ‡ Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom and the § Procter & Gamble Co. , Cincinnati, Ohio 45253 The secretion of IL-1 is […]
Is Isolated Low HDL-C a CVD Risk Factor?: New Insights from the Framingham Offspring Study Jacquelaine Bartlett, MS,#1 Irene M. Predazzi, PhD,#2 Scott M. Williams, PhD,1 William S. Bush, PhD, MS,3Yeunjung Kim, MD, MPH,4 Stephen Havas, MD, MPH, MS,5 Peter P. Toth, MD, PhD,6 Sergio Fazio, MD, PhD,2 andMichael Miller, MD7 Abstract Background— While the inverse association between high-density lipoprotein […]
HDL cholesterol and bone mineral density: Is there a genetic link? Cheryl L. Ackert-Bicknell Abstract Overwhelming evidence has linked cardiovascular disease and osteoporosis, but the shared root cause of these two diseases of the elderly remains unknown. Low levels of high-density lipoprotein cholesterol (HDL) and bone mineral density (BMD) are risk factors for cardiovascular […]