Calcium Signaling and Cardiac Arrhythmias

Calcium Signaling and Cardiac Arrhythmias

Andrew P. Landstrom, Dobromir Dobrev and Xander H.T. Wehrens Abstract There has been a significant progress in our understanding of the molecular mechanisms by which calcium (Ca 2+ ) ions mediate various types of cardiac arrhythmias. A growing list of inherited gene defects can cause potentially lethal cardiac arrhythmia syndromes, including catecholaminergic polymorphic ventricular tachycardia, […]

Altered calcium signaling in cancer cells

Altered calcium signaling in cancer cells

Teneale A. Stewart, Kunsala T.D.S. Yapa, Gregory R. Monteith Abstract It is the nature of the calcium signal, as determined by the coordinated activity of a suite of calcium channels, pumps, exchangers and binding proteins that ultimately guides a cell’s fate. Deregulation of the calcium signal is often deleterious and has been linked to each […]

Calcium Channels and Pumps in Viral Infections

Calcium Channels and Pumps in Viral Infections

Xingjuan Chen 1,2, Ruiyuan Cao 2,* and Wu Zhong 2,* 1 Institute of Medical Research, Northwestern Polytechnical University, Xi’an 710072, China; xjchen@nwpu.edu.cn 2 National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China * Correspondence: 21cc@163.com (R.C.); zhongwu@bmi.ac.cn (W.Z.) Received: 11 December 2019; Accepted: 24 December 2019; Published: […]

Calcium signalling and cancer cell growth

Calcium signalling and cancer cell growth

T. CAPIOD1, Y. SHUBA2, R. SKRYMA1 and N. PREVARSKAYA1 1INSERM U800, Laboratoire de Physiologie Cellulaire, Université des Sciences et Technologies Lille 1, 59655 Villeneuve d’Ascq Cedex, France 2Bogomoletz Institute of Physiology, NASU, Bogomoletz Str, 4, 01024 Kiev-24, Ukraine   Abstract Cancer is caused by defects in the mechanisms underlying cell proliferation and cell death. Calcium […]

Regulation of calcium signaling in lung cancer

Haihong Yang, Qi Zhang, Jianxing He, Wenju Lu State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, PR China   ABSTRACT Lung cancer is the most common malignant tumor in the world. Calcium is a ubiquitous cellular signal, which is crucial in cancer. This review presents regulation of […]