Altered calcium signaling in cancer cells

Altered calcium signaling in cancer cells

Teneale A. Stewart, Kunsala T.D.S. Yapa, Gregory R. Monteith Abstract It is the nature of the calcium signal, as determined by the coordinated activity of a suite of calcium channels, pumps, exchangers and binding proteins that ultimately guides a cell’s fate. Deregulation of the calcium signal is often deleterious and has been linked to each […]

Discovery of Calcium as a Biofilm-Promoting Signal for Vibrio fischeri Reveals New Phenotypes and Underlying Regulatory Complexity

Discovery of Calcium as a Biofilm-Promoting Signal for Vibrio fischeri Reveals New Phenotypes and Underlying Regulatory Complexity

Alice H. Tischler, Louise Lie, Cecilia M. Thompson, Karen L. Visick George O’Toole, Editor ABSTRACT Vibrio fischeri uses biofilm formation to promote symbiotic colonization of its squid host, Euprymna scolopes. Control over biofilm formation is exerted at the level of transcription of the symbiosis polysaccharide (syp) locus by a complex set of two-component regulators. Biofilm formation can be induced […]

Modeling and Analysis of Calcium Signaling Events Leading to Long-Term Depression in Cerebellar Purkinje Cells

Modeling and Analysis of Calcium Signaling Events Leading to Long-Term Depression in Cerebellar Purkinje Cells

Nicholas Hernjak, Boris M. Slepchenko, Kathleen Fernald, Charles C. Fink, Dale Fortin, Ion I. Moraru, James Watras, and Leslie M. Loew Center for Cell Analysis and Modeling, University of Connecticut Health Center, armington, Connecticut Abstract Modeling and simulation of the calcium signaling events that precede long-term depression of synaptic activity in cerebellar Purkinje cells are […]

Role of Residual Calcium in Synaptic Depression and Posttetanic Potentiation: Fast and Slow Calcium Signaling in Nerve Terminals

Role of Residual Calcium in Synaptic Depression and Posttetanic Potentiation: Fast and Slow Calcium Signaling in Nerve Terminals

Dieter Swandulla,+ Michael Hans,+ Karl Zipser,+* and George J. Augustine+5 *Max-Planck-lnstitut fur Biophysikalische Chemie Am Fassberg D-3400 Gottingen Germany +Marine Biological Laboratory Woods Hole, Massachusetts 02543 SDepartment of Neurobiology Duke University Medical Center Durham, North Carolina 27710 Summary Trains of action potentials evoked rises in presynaptic Ca2+ concentration ([Caz+jJ at the squid giant synapse. These […]

Early pre- and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice

Early pre- and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer’s disease mice

Shreaya Chakroborty, Joyce Kim, Corinne Schneider, Christopher Jacobson, Jordi Molgó, and Grace E. Stutzmann1. Department of Neuroscience, Rosalind Franklin University / The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 600642. CNRS, Institut de Neurobiologie Alfred Fessard, FRC2118, Laboratoire de Neurobiologie et Développement, UPR 3294, 91198 Gif-sur-Yvette Cedex, France Abstract Alzheimer’s disease (AD)-linked […]

Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling

Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling

Carlotta Giorgi1,, Massimo Bonora1,, Sonia Missiroli1, Federica Poletti1, Fabian Galindo Ramirez2,3, Giampaolo Morciano1, Claudia Morganti1, Pier Paolo Pandolfi4,Fabio Mammano2 and Paolo Pinton1 1 Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biologyand LTTA center, University of Ferrara, Ferrara, Italy 2 Department of Physics and Astronomy, University of Padua, and Venetian […]