SAC(Sigma Anti-bonding Calcium Carbonate) Study with GCaMP on Zebra Fish By Prof. Sandra Rieger, Sylvester Comprehensive Cancer Center, University of Miami, Jan. 2021 As shown in the following figure, D depicts the fluorescent cells which were analyzed. Zebrafish transient microinjections result was in a mosaic expression; therefore, only some cells expressed the GCaMP. A red […]
Guanyu Hao, Zhi Ping Xu* and Li Li * Abstract
A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration between IRB Barcelona, the Moffitt Cancer Center, and the University of Maryland, has been published in Nature Communications.
Katharine A. White1, Bree K. Grillo-Hill2 and Diane L. Barber1,* ABSTRACT Dysregulated pH is a common characteristic of cancer cells, as they have an increased intracellular pH (pHi) and a decreased extracellular pH (pHe) compared with normal cells. Recent work has expanded our knowledge of how dysregulated pH dynamics influences cancer cell behaviors, including […]
Alice H. Tischler, Louise Lie, Cecilia M. Thompson, Karen L. Visick George O’Toole, Editor ABSTRACT Vibrio fischeri uses biofilm formation to promote symbiotic colonization of its squid host, Euprymna scolopes. Control over biofilm formation is exerted at the level of transcription of the symbiosis polysaccharide (syp) locus by a complex set of two-component regulators. Biofilm formation can be induced […]
Vineet D. Menachery1, Boyd L. Yount Jr1, Kari Debbink1,2, Sudhakar Agnihothram3, Lisa E. Gralinski1, Jessica A. Plante1, Rachel L. Graham1, Trevor Scobey1, Xing-Yi Ge8, Eric F. Donaldson1, Scott H. Randell4,5, Antonio Lanzavecchia6, Wayne A. Marasco7, Zhengli-Li Shi8, and Ralph S. Baric1, Abstract The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East […]
Yu Chen|Qianyun Liu|Deyin Guo Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China Center for Infection and Immunity Study, School of Medicine, Sun Yat‐sen University, Guangzhou, China Abstract The recent emergence of a novel corona virus (2019‐nCoV), which is causing an out break of unusual viral pneumonia in […]
Viruses originate from RNAs. The sugar in RNA is ribose sugar and is the phosphates based, and they react in the nucleotides to form an ester bond. While not inside a cell or in the process of cell infection, viruses exist as an independent particle known as virions or virus particles. The way the virus […]
Matthew G. Drake1*, Elizabeth R. Bivins-Smith1*, Becky J. Proskocil1, Zhenying Nie1, Gregory D. Scott2, James J. Lee3,Nancy A. Lee4, Allison D. Fryer1, and David B. Jacoby1 Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon; 3 Department of Biochemistry and Molecular Biology, Division of Pulmonary Medicine, and 4 Department of […]
Nutrients 2013, 5, 3964-3974; doi:10.3390 / nu5103964 / ISSN 2072-6643 Abstract: Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or […]