SARS-CoV-2 Infection Induces
Inflammatory Bone Loss in hamsters

SARS-CoV-2 Infection Induces<br>Inflammatory Bone Loss in hamsters

Wei Qiao, Hui En Lau, Huizhi Xie, Vincent Kwok-Man Poon, Chris Chung-Sing Chan,Hin Chu, Shuofeng Yuan, Terrence Tsz-Tai Yuen, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Chris Chun-Yiu Chan, Jian-Piao Cai, Cuiting Luo, Kwok-Yong Yuen, Kenneth Man-Chee Cheung, Jasper Fuk-Woo Chan & Kelvin Wai-Kwok Yeung Abstract Extrapulmonary complications of different organ systems have been increasingly recognized […]

Sigma Anti-Bonding Calcium Carbonate (SAC) cream enhances the wound healing process

Sigma Anti-Bonding Calcium Carbonate (SAC) cream enhances the wound healing process

JIHWAN SONG , Syed Hassan Mehdi, Sae Woong Oh, Jongsung Lee, Paul K Lee, Alex Lee, Yong Gu Lee, and Donghoon Yoon Abstract Sigma Anti-Bonding Molecule Calcium Carbonate (SAC) is a chemically modified calcium carbonate with a unique weak bonding structure that significantly increases the calcium absorbing rate in our body. It can influence environmental […]

Life Expectancy in Patients Treated for Osteoporosis: Observational Cohort Study Using National Danish Prescription Data

Life Expectancy in Patients Treated for Osteoporosis: Observational Cohort Study Using National Danish Prescription Data

Bo Abrahamsen, Clive Osmond and Cyrus Cooper Abstract Osteoporosis is a chronic disease, carrying an elevated risk of fractures, morbidity, and death. Long-term treatment may be required, but the long-term risks with osteoporosis drugs remain incompletely understood. The competing risk of death may be a barrier to treating the oldest, yet this may not be […]

Microbiome in the Gut-Skin Axis in Atopic Dermatitis

Microbiome in the Gut-Skin Axis in Atopic Dermatitis

So-Yeon Lee, Eun Lee, Yoon Mee Park, Soo-Jong Hong Abstract The microbiome is vital for immune system development and homeostasis. Changes in microbial composition and function, termed dysbiosis, in the skin and the gut have recently been linked to alterations in immune responses and to the development of skin diseases, such as atopic dermatitis (AD). […]

Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression

Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression

Mi Nam Lee, Hee-Su Hwang, Sin-Hye Oh, Amir Roshanzadeh, Jung-Woo Kim, Ju Han Song, Eung-Sam Kim and Jeong-Tae Koh Abstract Supplementation of mesenchymal stem cells (MSCs) at sites of bone resorption is required for bone homeostasis because of the non-proliferation and short lifespan properties of the osteoblasts. Calcium ions (Ca 2+ ) are released from […]

Calcium Signaling and Cardiac Arrhythmias

Calcium Signaling and Cardiac Arrhythmias

Andrew P. Landstrom, Dobromir Dobrev and Xander H.T. Wehrens Abstract There has been a significant progress in our understanding of the molecular mechanisms by which calcium (Ca 2+ ) ions mediate various types of cardiac arrhythmias. A growing list of inherited gene defects can cause potentially lethal cardiac arrhythmia syndromes, including catecholaminergic polymorphic ventricular tachycardia, […]

Association between the gut microbiota and mineral metabolism

Association between the gut microbiota and mineral metabolism

Katarzyna Skrypnik and Joanna Suliburska Abstract The aim of this review is to present the most recent scientific evidence of interactions between the intestinal microbiota and minerals,andtheeffectofthisinteractiononthehealthofthehost.TheWebofSciencedatabasefromtheyears2013–2017on thistopicwasreviewed.Numerousinvitrostudieshaveshownthatironsignificantlyaffectstheintestinalmicrobiota.However, Bifidobacteriaceaearecapableofbindingironinthelargeintestine,therebylimitingtheformationoffreeradicalssynthesized inthepresenceofiron,andthusreducingtheriskofcolorectalcancer.Animalstudieshaverevealedthatsupplementationwith probiotics, prebiotics and synbiotics has a significant effect on bone calcium, phosphate and bone metabolism. The dynamic interaction between microbiota and zinc was shown. Human […]

The Renin-Angiotensin-Aldosterone System and Calcium-Regulatory Hormones

The Renin-Angiotensin-Aldosterone System and Calcium-Regulatory Hormones

Anand Vaidya, MD MMSc, Jenifer M. Brown, MD, and Jonathan S. Williams, MD MMSc Abstract There is increasing evidence of a clinically relevant interplay between the renin-angiotensin-aldosterone system and calcium regulatory systems. Classically, the former is considered a key regulator of sodium and volume homeostasis while the latter is most often associated with skeletal health. […]