Risk of High Dietary Calcium for Arterial Calcification in Older Adults -Review

Risk of High Dietary Calcium for Arterial Calcification in Older Adults -Review

Nutrients 2013, 5, 3964-3974; doi:10.3390 / nu5103964 / ISSN 2072-6643 Abstract:   Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or […]

Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis (Review)

Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis (Review)

Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis (Review) Laura Toxqui and M. Pilar Vaquero * Abstract: Iron is essential in oxygen transport and participates in many enzymatic systems in the body, with important roles in collagen synthesis and vitamin D metabolism. The relationship between iron and bone health comes from […]

Calcium orchestrates apoptosis

Calcium orchestrates apoptosis

Mark P.Mattson and Sic L. Chan Apoptosis is a feature of many diseases and is critical for the sculpting and maintenance of tissues. New work demonstrates that calcium released from the endoplasmic reticulum synchronizes the mass exodus of cytochrome c from the mitochondria, a phenomenon that coordinates apoptosis. One unresolved problem in cell biology has […]

Effects of Risedronate Treatment on Vertebral and Nonvertebral Fractures

in Women With Postmenopausal Osteoporosis – A Randomized Controlled Trial Context Risedronate, a potent bisphosphonate, has been shown to be effective in the treatment of Paget disease of bone and other metabolic bone diseases but, to our knowledge, it has not been evaluated in the treatment of established postmenopausal osteoporosis. Objective To test the efficacy […]