The Renin-Angiotensin-Aldosterone System and Calcium-Regulatory Hormones

The Renin-Angiotensin-Aldosterone System and Calcium-Regulatory Hormones

Anand Vaidya, MD MMSc, Jenifer M. Brown, MD, and Jonathan S. Williams, MD MMSc Abstract There is increasing evidence of a clinically relevant interplay between the renin-angiotensin-aldosterone system and calcium regulatory systems. Classically, the former is considered a key regulator of sodium and volume homeostasis while the latter is most often associated with skeletal health. […]

The importance of Ca2+ -dependent mechanisms for the initiation of the heartbeat

The importance of Ca<sup>2+</sup> -dependent mechanisms for the initiation of the heartbeat

Rebecca A. Capel and Derek A. Terrar* British Heart Foundation Centre of Research Excellence, Department of Pharmacology, University of Oxford, Oxford, UK   Mechanisms underlying pacemaker activity in the sinus node remain controversial, with some ascribing a dominant role to timing events in the surface membrane (“membrane clock”) and others to uptake and release of […]

Viral calciomics: Interplays between Ca2+ and virus

Viral calciomics: Interplays between Ca<sup>2+</sup> and virus

Yubin Zhoua, Teryl K. Freyb,*, and Jenny J. Yanga,** aDepartment of Chemistry, Georgia State University, 50 Decatur St., Atlanta, GA 30303 USA bDepartment of Biology, Georgia State University, 50 Decatur St., Atlanta, GA 30303 USA   Abstract Ca2+ is one of the most universal and versatile signalling molecules and is involved in almost every aspect […]

Discovery of Calcium as a Biofilm-Promoting Signal for Vibrio fischeri Reveals New Phenotypes and Underlying Regulatory Complexity

Discovery of Calcium as a Biofilm-Promoting Signal for Vibrio fischeri Reveals New Phenotypes and Underlying Regulatory Complexity

Alice H. Tischler, Louise Lie, Cecilia M. Thompson, Karen L. Visick George O’Toole, Editor ABSTRACT Vibrio fischeri uses biofilm formation to promote symbiotic colonization of its squid host, Euprymna scolopes. Control over biofilm formation is exerted at the level of transcription of the symbiosis polysaccharide (syp) locus by a complex set of two-component regulators. Biofilm formation can be induced […]

SAC calcium and Virus

SAC calcium and Virus

Viruses originate from RNAs. The sugar in RNA is ribose sugar and is the phosphates based, and they react in the nucleotides to form an ester bond. While not inside a cell or in the process of cell infection, viruses exist as an independent particle known as virions or virus particles. The way the virus […]

Risk of High Dietary Calcium for Arterial Calcification in Older Adults -Review

Risk of High Dietary Calcium for Arterial Calcification in Older Adults -Review

Nutrients 2013, 5, 3964-3974; doi:10.3390 / nu5103964 / ISSN 2072-6643 Abstract:   Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or […]

Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways

Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways

Biochimica et Biophysica Acta (BBA) – Molecular Cell Research Volume 1865, Issue 11, Part B, November 2018, Pages 1718-1732 Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways☆ Author links open overlay panelRachel L.NguyenabYuliya V.MedvedevaabdTejasvi E.AyyagariabGalinaSchmunkbJohn JayGargusabc a Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA b […]

Calcium aids chromosome condensation prior to cell division

Calcium aids chromosome condensation prior to cell division

Science News from research organizations Calcium aids chromosome condensation prior to cell division Date: December 27, 2016 Source: Osaka University Summary: New research reveals role for calcium ions in chromosome condensation during mitosis; high-resolution imaging of living cells reveals compact, globular chromosomes in the presence of calcium that became fibrous and expand in its absence. […]

Modeling and Analysis of Calcium Signaling Events Leading to Long-Term Depression in Cerebellar Purkinje Cells

Modeling and Analysis of Calcium Signaling Events Leading to Long-Term Depression in Cerebellar Purkinje Cells

Nicholas Hernjak, Boris M. Slepchenko, Kathleen Fernald, Charles C. Fink, Dale Fortin, Ion I. Moraru, James Watras, and Leslie M. Loew Center for Cell Analysis and Modeling, University of Connecticut Health Center, armington, Connecticut Abstract Modeling and simulation of the calcium signaling events that precede long-term depression of synaptic activity in cerebellar Purkinje cells are […]

Role of Residual Calcium in Synaptic Depression and Posttetanic Potentiation: Fast and Slow Calcium Signaling in Nerve Terminals

Role of Residual Calcium in Synaptic Depression and Posttetanic Potentiation: Fast and Slow Calcium Signaling in Nerve Terminals

Dieter Swandulla,+ Michael Hans,+ Karl Zipser,+* and George J. Augustine+5 *Max-Planck-lnstitut fur Biophysikalische Chemie Am Fassberg D-3400 Gottingen Germany +Marine Biological Laboratory Woods Hole, Massachusetts 02543 SDepartment of Neurobiology Duke University Medical Center Durham, North Carolina 27710 Summary Trains of action potentials evoked rises in presynaptic Ca2+ concentration ([Caz+jJ at the squid giant synapse. These […]