Guanyu Hao, Zhi Ping Xu* and Li Li * Abstract
A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration between IRB Barcelona, the Moffitt Cancer Center, and the University of Maryland, has been published in Nature Communications.
Katharine A. White1, Bree K. Grillo-Hill2 and Diane L. Barber1,* ABSTRACT Dysregulated pH is a common characteristic of cancer cells, as they have an increased intracellular pH (pHi) and a decreased extracellular pH (pHe) compared with normal cells. Recent work has expanded our knowledge of how dysregulated pH dynamics influences cancer cell behaviors, including […]
Gordon L. Klein Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch and Shriners Burns Hospital, Galveston, TX 77555-0165, USA; email@example.com; Tel.: +1-409-747-5700; Fax: +1-409-770-6919 Received: 28 June 2018; Accepted: 27 July 2018; Published: 1 August 2018 Abstract: The aim of this mini-review is to discuss the role of calcium in the […]