ChingWooen Sze 1 and Yee-Joo Tan 1;2;* 1 Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System (NUHS), National University of Singapore, MD4, Level 3, 5 Science Drive 2, Singapore 117597, Singapore; E-Mail: micscw@nus.edu.sg 2 Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A * STAR), Singapore […]
Author Archives: cbhi
Calcium Channels and Pumps in Viral Infections
Xingjuan Chen 1,2, Ruiyuan Cao 2,* and Wu Zhong 2,* 1 Institute of Medical Research, Northwestern Polytechnical University, Xi’an 710072, China; xjchen@nwpu.edu.cn 2 National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China * Correspondence: 21cc@163.com (R.C.); zhongwu@bmi.ac.cn (W.Z.) Received: 11 December 2019; Accepted: 24 December 2019; Published: […]
Viral calciomics: Interplays between Ca2+ and virus
Yubin Zhoua, Teryl K. Freyb,*, and Jenny J. Yanga,** aDepartment of Chemistry, Georgia State University, 50 Decatur St., Atlanta, GA 30303 USA bDepartment of Biology, Georgia State University, 50 Decatur St., Atlanta, GA 30303 USA Abstract Ca2+ is one of the most universal and versatile signalling molecules and is involved in almost every aspect […]
Discovery of Calcium as a Biofilm-Promoting Signal for Vibrio fischeri Reveals New Phenotypes and Underlying Regulatory Complexity
Alice H. Tischler, Louise Lie, Cecilia M. Thompson, Karen L. Visick George O’Toole, Editor ABSTRACT Vibrio fischeri uses biofilm formation to promote symbiotic colonization of its squid host, Euprymna scolopes. Control over biofilm formation is exerted at the level of transcription of the symbiosis polysaccharide (syp) locus by a complex set of two-component regulators. Biofilm formation can be induced […]
SARS-like cluster of circulating bat coronavirus pose threat for human emergence
Vineet D. Menachery1, Boyd L. Yount Jr1, Kari Debbink1,2, Sudhakar Agnihothram3, Lisa E. Gralinski1, Jessica A. Plante1, Rachel L. Graham1, Trevor Scobey1, Xing-Yi Ge8, Eric F. Donaldson1, Scott H. Randell4,5, Antonio Lanzavecchia6, Wayne A. Marasco7, Zhengli-Li Shi8, and Ralph S. Baric1, Abstract The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East […]
Emerging corona viruses: Genome structure, replication, and pathogenesis
Yu Chen|Qianyun Liu|Deyin Guo Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China Center for Infection and Immunity Study, School of Medicine, Sun Yat‐sen University, Guangzhou, China Abstract The recent emergence of a novel corona virus (2019‐nCoV), which is causing an out break of unusual viral pneumonia in […]
SAC calcium and Virus
Viruses originate from RNAs. The sugar in RNA is ribose sugar and is the phosphates based, and they react in the nucleotides to form an ester bond. While not inside a cell or in the process of cell infection, viruses exist as an independent particle known as virions or virus particles. The way the virus […]
Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus
Matthew G. Drake1*, Elizabeth R. Bivins-Smith1*, Becky J. Proskocil1, Zhenying Nie1, Gregory D. Scott2, James J. Lee3,Nancy A. Lee4, Allison D. Fryer1, and David B. Jacoby1 Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, Portland, Oregon; 3 Department of Biochemistry and Molecular Biology, Division of Pulmonary Medicine, and 4 Department of […]
Risk of High Dietary Calcium for Arterial Calcification in Older Adults -Review
Nutrients 2013, 5, 3964-3974; doi:10.3390 / nu5103964 / ISSN 2072-6643 Abstract: Concern has recently arisen about the potential adverse effects of excessive calcium intakes, i.e., calcium loading from supplements, on arterial calcification and risks of cardiovascular diseases (CVD) in older adults. Published reports that high calcium intakes in free-living adults have relatively little or […]
Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis (Review)
Chronic Iron Deficiency as an Emerging Risk Factor for Osteoporosis: A Hypothesis (Review) Laura Toxqui and M. Pilar Vaquero * Abstract: Iron is essential in oxygen transport and participates in many enzymatic systems in the body, with important roles in collagen synthesis and vitamin D metabolism. The relationship between iron and bone health comes from […]