Makarand Deo1, Seth H Weinberg2 and Patrick M Boyle3
1Department of Engineering, Norfolk State University, Norfolk, VA, USA. 2Department of
Biomedical Engineering, School of Engineering, Virginia Commonwealth University,
Richmond, VA, USA. 3Department of Biomedical Engineering, Johns Hopkins University,
Baltimore, MD, USA.
AIMS AND SCOPE This Special Collection will gather all studies highlighting recent advances in theoretical and experimental studies of arrhythmia, with a specific focus on research seeking to elucidate links between calcium homeostasis in cardiac cells and organ-scale disruption of heart rhythm.
Cardiac arrhythmia, caused by disruption of the coordinated electrical activity of heart, is among the leading causes of sudden cardiac death in United States.1 Intracellular calcium dynamics in cardiac cells have been recognized as an important contributor in life-threatening ventricular arrhythmia (ventricular tachycardia and ventricular fibrillation)2,3 as well as increasingly prevalent atrial arrhythmias (atrial fibrillation [AF] and flutter).4,5 We have assembled this special supplement which highlights recent advances in theoretical and experimental studies of arrhythmia, with a specific focus on research seeking to elucidate links between calcium homeostasis in cardiac cells and organ-scale disruption of heart rhythm.
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