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Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function

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Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function

Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function     Highlights BMF variation impacts the gut microbiota and blood metabolome in a healthy cohort Aberrant BMF associates with microbially derived toxins in blood and with inflammation Indoxyl sulfate linked to constipation and negatively associates with kidney function Diet, […]

Cell Host & Microbe

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Cell Host & Microbe

Breastmilk Feeding Practices Are Associated with the Co-Occurrence of Bacteria in Mothers’ Milk and the Infant Gut: the CHILD Cohort Study Highlights – Breastfeeding exclusivity and duration strongly influence infant gut microbiota – A few bacterial species co-occur in mothers’ milk and their infants’ stool – This co-occurrence is reduced when breastmilk is pumped and […]

Unraveling the role of Calcium ions in the mechanical properties of individual collagen fibrils

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Unraveling the role of Calcium ions in the mechanical properties of individual collagen fibrils

Abstract Collagen, the dominating material in the extracellular matrix, provides the strength, elasticity and mechanical stability to the organisms. The mechanical property of collagen is mainly dominated by its surrounding environments. However, the variation and origin of the mechanics of collagen fibril under different concentrations of calcium ions (χCa) remains unknown. By using the atomic […]

SAC technology effects on skin

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SAC technology effects on skin

The structure of human skin includes the epidermis, which protects against environmental factors, and the dermis, containing proteins like collagen and elastin for strength and elasticity. Aging skin experiences thinning of the epidermis and reduction in dermal proteins, leading to sagging, decreased elasticity, and dryness. The subcutaneous fat layer also diminishes, causing further sagging. SAC […]

The importance of Ca2+:dependent mechanisms for the initiation of the heartbeat

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The importance of Ca2+:dependent mechanisms for the initiation of the heartbeat

by Rebecca A. Capel and Derek A. Terrar* *British Heart Foundation Centre of Research Excellence, Department of Pharmacology, University of Oxford, Oxford, UK It reviews the roles of calcium in pacemaker activity of the sino-atrial node (SAN). It discusses the ongoing debate between the “membrane clock” and “calcium clock” theories, emphasizing the diverse and crucial […]