Calcium Signaling for Bone and Systemic Repair
2.5 mg/day offers measurable BMD gains
Experience the Next Generation of Calcium Therapy
SAC®(Sigma Anti-Bonding Calcium) is a calcium carbonate, that is produced in a unique process, using natural Canadian small oyster shells as essential raw material. The Calcium carbonate has a Sigma Anti-Bonding Molecule with a weak bonding force. This property makes the molecule dissolve quickly and allows it to be absorbed into cells more readily. SAC® produces Active Calcium Ca++ during its metabolism in the body. SAC® functions as a stimulation of the body and helps metabolism; this results in a healthier metabolic system and stronger bone structure.
What is SAC®?
SAC® (Sigma Anti‑Bonding Calcium) is a highly bioavailable calcium derived from natural oyster shell calcium carbonate, engineered to be 26× more soluble than standard forms.
- Remains ionized in the bloodstream (Ca²⁺)
- Passively absorbed — no need for vitamin D or peptides
- Stimulates PTH and calcitonin, supporting active bone remodeling
- Backed by preclinical studies showing restoration of bone mineral density
What is AIC®?
AIC® (Anti‑Orbital Ionic Calcium) is a medical-grade calcium that undergoes an ionization process to strip electrons from the calcium atom’s orbital shell, resulting in ultra-pure, free Ca²⁺ ions.
- 99.9% purity — highest ionic activity
- Used in thousands of clinics globally
- Optimized for maximum absorption and cellular uptake
Together, SAC® and AIC® maximize bioavailability and physiological impact.
Why It Matters to Your Patients
- Superior absorption without GI burden
- Rapid physiological response — not just supplementation, but metabolic activation
- Potential applications in:
- Osteoporosis
- Bone regeneration
- Mitochondrial function support
- Calcium-related metabolic disorders
Why Work with Pronuvia?
Pronuvia is the exclusive U.S. distributor for SAC® and AIC® technologies through CBHI.
We support healthcare professionals with:
- Direct access to clinical‑grade SAC®/AIC® products
- Scientific literature and training
- Priority ordering and physician-only pricing
Take the Next Step
For more information, please email us at info@pronuvia.com or call us at (800) 568-2982. You’re also welcome to visit Pronuvia online to learn more information.
