Direct Therapeutic Applications of Calcium Electroporation to Effectively Induce Tumor Necrosis

Stine Krog Frandsen1, Hanne Gissel2, Pernille Hojman3, Trine Tramm4, Jens Eriksen1,5, and Julie Gehl1 Abstract Electroporation of cells with short, high-voltage pulses causes a transient permeabilization of cell membranes that permits passage of otherwise nonpermeating ions and molecules. In this study, we illustrate how ¬†lectroporation with isotonic calcium can achieve highly effective cancer cell kill […]