Diabetes Wound Healing Second Trial

–Purpose : From previous experiments, SAC cream improves the wound healing process in normal mid-age mice. In this study, We assume SAC cream may improve the wound healing process in diabetic mice having impaired wound healing.

1.Animal

• a.Ob/Ob mice (born on 12.13.22, 8 weeks based on made wound day)
• b.Made wounds with 8mm punch biopsy (at 02.07.23)

2.Group

• a.4 female ob/ob mice are separated in each cage (at 02.03.23)
• b.Experiment started at 02.07.23
• c.Each mouse had two wounds on each side, and each group has formed by two mice. Tegaderm Covered Wound (Called Open Wound) / SAC cream

3.Work

• a.Applied cream and Put a new Tegaderm every day from the day made the wound
• b.Every day measurement and take a picture
• c.Biopsies were taken Pre-Trt, Post 1 (3 days after closure), Post 2 (10 days after closure),  Post 3 (20 days after closure)