Endoplasmic-Reticulum Calcium Depletion and Disease

Endoplasmic-Reticulum Calcium Depletion and Disease

Djalila Mekahli, Geert Bultynck, Jan B. Parys, Humbert De Smedt, and Ludwig Missiaen Laboratory of Molecular and Cellular Signaling, Department of Molecular Cell Biology, K.U.Leuven Campus Gasthuisberg O&N I, Herestraat 49, 3000 Leuven, Belgium Correspondence: Ludwig.Missiaen@med.kuleuven.be The endoplasmic reticulum (ER) as an intracellular Ca²+ store not only sets up cytosolic Ca²+ signals but, among other functions, […]

Dairy products, calcium, and prostate cancer risk in the Physicians’ Health Study

Dairy products, calcium, and prostate cancer risk in the Physicians’ Health Study June M Chan, Meir J Stampfer, Jing Ma, Peter H Gann, J Michael Gaziano, and Edward L Giovannucci ABSTRACT Background: A high calcium intake, mainly from dairy products, may increase prostate cancer risk by lowering concentrations of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], a hormone thought […]